MaterialsAtlas Synthesis Resource
MIT OCW organic chemistry synthesis training
Procedure and training source portalssource portalall synthesis researcherschemical synthesisgraduate trainingMIT OCW Organic Chemistryprocedure sourcetraining sourceopen resourceMITOCWorganic
MIT OCW organic chemistry synthesis training is a ChemistryAtlas synthesis guide card for procedure and training source portals. It focuses on finding authoritative procedures, examples, and training material quickly.
- Start with the linked source: MIT OCW Organic Chemistry.
- Compare at least two literature precedents before using the chemistry on a valuable substrate.
- Record reagent equivalents, concentration, temperature, atmosphere, time, workup, purification, yield, and characterization.
- When this topic is useful in a synthesis plan.
- Which variables usually control success or failure.
- What evidence is needed before trusting the product assignment.
Characterization expectation: include at minimum 1H NMR, 13C NMR when applicable, LC-MS or HRMS, and purity evidence appropriate to the product class.
Safety expectation: review SDS and incompatibilities, keep scale conservative during scouting, and document quench and waste handling before running the reaction.
Recommended level: all synthesis researchers. Resource type: source portal.
Citation: MIT OpenCourseWare organic chemistry courses.